Localization of intracranial electrodes is critical for invasive epilepsy evaluations and to confirm or not confirm the epileptic zone hypothesis. Various methods exist using various open-source and commercial software. Here is one method using some latest updates to the Brainstorm software.
Required imaging:
- Pre-implantation T1 without contrast 1mm 3D volume scan
- Post-implantation CT scan without contrast 1mm 3D volume scan
Assuming you are already familiar with Brainstorm and have already created anatomy files using Freesurfer:
Choose Freesurfer folder
Change file type to Freesurfer
Set fiducial points & compute MNI coordinates
Convert CT to .nii.gz first with MRIcroGL (drag and drop)
Import CT by selecting ‘Import MRI’
Go to CT, Display, Overlay on default MRI (MRI Viewer)
Right click, Electrodes, Set electrode position
http://neuroimage.usc.edu/brainstorm/